Clinical trial · Observational
UCSF PANC Cyst Registry
Population-Based Analysis of Neoplastic Changes in Cystic Lesions of the Pancreas.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors to pancreatic cancer, and thus pose a substantial risk, however, the vast majority are benign. Increased detection of pancreatic cysts provides an opportunity to diagnose pancreatic malignancy at an early, curable stage yet also increases the potential to over-treat clinically insignificant lesions. This presents a clinical challenge to prevent unnecessary resection of indolent disease, with associated risks of infections, bleeding, diabetes, and costly disability. Unfortunately, there is little information on the epidemiology and natural history of pancreatic cysts to help guide management.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Intraductal Papillary Mucinous Neoplasm | Pancreatic Intraductal Papillary Mucinous Neoplasm | ALIAS | 0.90 |
| Mucinous Cyst | — | UNRESOLVED | — |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Pancreatic Cyst | — | UNRESOLVED | — |
| Pancreatic Diseases | — | UNRESOLVED | — |
| Pancreatic Ductal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Pancreatic Intraductal Papillary Mucinous Neoplasm | Pancreatic Intraductal Papillary Mucinous Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pancreatic Neoplasms |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Survey | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Retrospective
- description
- The registry will be populated with a retrospective cohort of patients previously identified as having pancreatic cysts.
- label
- Prospective
- description
- The prospectively enrolled patients in this study are the primary population of interest.
- interventionNames
- Other: Survey
Primary outcomes (2)
- measure
- Cancer
- timeFrame
- 1-10 years
- description
- While not the primary outcome measure, the development of cancer from a pancreatic cyst is a critically important study endpoint, which the investigators do not expect to be frequent occurrence.
- measure
- Indolency
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * The inclusion criteria for this study are intentionally broad. Eligible patients for prospective enrollment will include * Adults ≥ 30 years of age * Have a radiographic or endoscopic diagnosis of at least one pancreatic cysts regardless of treatment status, * No history of pancreatic cancer, * Can speak and read English, * Have access to a computer or mobile device (\~95% of U.S. population); and * Are able to complete an electronic informed consent. Exclusion Criteria: * Patients who don't speak English, * Don't have access to a computer or mobile device; or * Patients who have a cancer diagnosis.
References
Publications (0)
Data not yet available