Clinical trial · Observational
Emergency Curative Resection of Colorectal Cancer
Emergency Curative Resection of Colorectal Cancer, Do it With Caution. A Comparative Case Series
NCT04288284CI-TRIAL-00043712completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The feasibility and efficacy of emergency curative resection of complicated colorectal cancer is still controversial. This prospective study aim is to assess surgical and oncologic outcomes after emergency compared to elective curative resection of colorectal cancer
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Oncologic Complications and Emergencies | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Curative resection of colorectal cancer | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Emergency group
- description
- Patients presented to emergency by complicated colorectal cancer ( Obstruction, bleeding or perforation)
- interventionNames
- Procedure: Curative resection of colorectal cancer
- label
- Elective group
- description
- Patients presented with uncomplicated colorectal cancer for resection treatment
- interventionNames
- Procedure: Curative resection of colorectal cancer
Primary outcomes (3)
- measure
- Adequate oncologic resection
- timeFrame
- histopathological assessment of surgical specimens within 2 weeks postoperative
- description
- Negative resection margins + adequate lymphadenectomy ( Lymph Nodes retrieved \> 12)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * All patients presented with Potentially operable colorectal cancer * No clinical or radiological evidence of metastatic disease Exclusion Criteria: * Patients received preoperative chemoradiation * Patients with clinical or radiological evidence of metastatic disease * Patients with intraoperative evidence of metastatic disease * Patients with intraoperative evidence of irresectable disease * Patients with incomplete follow up
References
Publications (3)
- BACKGROUNDGhazi S, Berg E, Lindblom A, Lindforss U; Low-Risk Colorectal Cancer Study Group. Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases. World J Surg Oncol. 2013 Jun 11;11:133. doi: 10.1186/1477-7819-11-133. PMID 23758762
- BACKGROUNDBiondo S, Marti-Rague J, Kreisler E, Pares D, Martin A, Navarro M, Pareja L, Jaurrieta E. A prospective study of outcomes of emergency and elective surgeries for complicated colonic cancer. Am J Surg. 2005 Apr;189(4):377-83. doi: 10.1016/j.amjsurg.2005.01.009. PMID 15820446
- BACKGROUNDKim J, Mittal R, Konyalian V, King J, Stamos MJ, Kumar RR. Outcome analysis of patients undergoing colorectal resection for emergent and elective indications. Am Surg. 2007 Oct;73(10):991-3. PMID 17983065