Clinical trial · Observational
Surgical Treatment of Chronic Neuropathic Pain
An Ambispective, Multicenter, Observational Registry Study of Patients Considering Surgical Treatment for Chronic Neuropathic Pain
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): The study was terminated due to lower than expected enrollment. The decision to terminate the study was not based on any safety or efficacy concerns.
Summary
Brief summary (as posted)
Observational registry study assessing the subject's pain history and the impact of surgery for the treatment of chronic neuropathic pain by comparing post-operative outcomes (pain level, pain medication usage, quality of life outcomes, and nerve functional outcome) to pre-operative levels.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Neuropathic Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgical Management of Neuroma | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Surgery
- description
- Participants who elect to undergo surgery for the treatment of their chronic, neuropathic pain
- interventionNames
- Procedure: Surgical Management of Neuroma
- label
- Non-surgery
- description
- Participants who elect to not have surgery for the treatment of their chronic, neuropathic pain
Primary outcomes (2)
- measure
- Performance: Change in Visual Analog Scale (VAS) for Pain Score at 1 year in both the surgery and non-surgery cohorts
- timeFrame
- 1 year
- description
- The Visual Analog Scale (VAS) for Pain is a patient reported outcomes scale whereby the patient indicates his/her current pain level by making a mark on a continuous horizontal 10-centimeter (100 millimeter) line. The distance from the 0 millimeter to the patient's mark corresponds to the amount of pain the subject is currently experiencing. VAS for Pain data are recorded as the number of millimeters from the left of the line to the patients mark across the range of 0-100 millimeters, with 0 millimeter representing no pain and 100 millimeters representing "the worst pain imaginable".
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Be Age ≥ 18 years 2. Have a documented diagnosis of chronic neuropathic pain 3. In the opinion of the investigator, be considered at the time of screening a likely candidate for surgical treatment of their neuropathic pain according to institutional standard of care. 4. Be willing to participate in data collection and all follow-up assessments throughout and for the entire duration of follow-up Exclusion Criteria: 1. Subjects who, in the opinion of the investigator, have not or likely will not complete the required follow-up assessments. 2. Subjects who are currently enrolled in another clinical trial; 3. Subjects who have undergone previous surgical treatment of pain from symptomatic neuroma in the target nerve(s); 4. Subjects who are undergoing treatment(s)/intervention(s) for other condition(s) which, in the opinion of the investigator, may confound assessment of pain or interfere with the study measurements.
References
Publications (0)
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