Clinical trial · Observational
Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
Long-term Ototoxicity in Cancer Survivors Treated With Chemotherapy and the Impact on Quality of Life
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This project aims to explore, in depth, the burden of hearing loss and tinnitus on cancer survivors. Using semi-structured interviews, audiograms and a variety of validated questionnaires, the specific impact ototoxicity has on quality of life will be investigated. From this, we can identify the specific needs of patients experiencing hearing loss and tinnitus following chemotherapy and develop a tailored and personalised support system.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Hearing Loss, Sensorineural | — | UNRESOLVED | — |
| Late Effect | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
| Tinnitus, Subjective | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hearing handicap inventory for adults/elderly (HHIA/HHIE) | Other | — | UNRESOLVED |
| High frequency audiometry | Diagnostic Test | — | UNRESOLVED |
| Short-Form 36-Item Questionnaire (SF-36) | Other | — | UNRESOLVED |
| Tinnitus handicap inventory (THI) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- People with ototoxicity
- description
- People living with and beyond who experience ototoxicity as a result of chemotherapy
- interventionNames
- Diagnostic Test: High frequency audiometry
- Other: Short-Form 36-Item Questionnaire (SF-36)
- Other: Hearing handicap inventory for adults/elderly (HHIA/HHIE)
- Other: Tinnitus handicap inventory (THI)
Primary outcomes (1)
- measure
- Prevalence of hearing loss
- timeFrame
- Between 0-5 years
- description
- High frequency audiogram
Secondary outcomes (3)
- measure
- Quality of life Questionnaire SF-36 (short-form 36 item)
- timeFrame
- Between 0-5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Has had platinum-based chemotherapy between 0-5 years ago * Has had at least 1 cycle- Was an adult (over 18) at the time of cancer diagnosis Exclusion Criteria: * Pre-existing hearing issues * Radiotherapy to the head and neck area
References
Publications (0)
Data not yet available