Clinical trial · Observational
Determination of ALDH1b1 and ALDH2 Polymorphisms Frequency in the Brazilian Population
NCT04270201CI-TRIAL-00051888ALDH2020unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A case-control study with oral squamous cell carcinoma (OSCC) patients from Instituto do Câncer do Estado de São Paulo (ICESP) and healthy volunteers. In this study, it will be collected saliva samples from both groups that will be submitted to sequencing analysis to evaluate the frequency of ALDH1b1 and ALDH2 polymorphisms in the Brazilian population. Also, correlate OSCC risk to alcohol consumption or smoke, by applied questionnaires.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Oral Squamous Cell Carcinoma (OSCC) | Oral Cavity Squamous Cell Carcinoma | ALIAS | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Saliva collection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Case group
- description
- OSCC patients (n = 60)
- interventionNames
- Other: Saliva collection
- label
- Control group
- description
- Healthy volunteers (n = 240)
- interventionNames
- Other: Saliva collection
Primary outcomes (1)
- measure
- Frequency of ALDH1b1 and ALDH2 polymorphisms
- timeFrame
- 1 year
- description
- Determine the frequency of ALDH1b1 and ALDH2 polymorphisms in OSCC patients and healthy volunteers.
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * OSCC diagnostic for case group * Able to read and sign the consent form. * Able for saliva collection. * Able to understand the applied questionnaires. Exclusion Criteria: * Unable to read and sign the consent form. * Unable for saliva collection. * Unable to understand the applied questionnaires. * OSCC patient's companions for healthy volunteers.
References
Publications (0)
Data not yet available
No reference posted for this study.