Clinical trial · Observational
Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions
NCT04267419CI-TRIAL-00043383completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
investigating the level of malondialdehyde (MDA) \& nitric oxide (NO) in saliva in oral premalignant and malignant lesions in order to determine their diagnostic value for the malignant and potentially malignant lesions.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukoplakia | — | UNRESOLVED | — |
| Oral Cancer | Malignant Lip and Oral Cavity Neoplasm | CURATED_BROADER | 0.80 |
| Oral Keratoses | — | UNRESOLVED | — |
| Oral Lichen Planus | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| salivary biomarker | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- label
- healthy Control
- description
- MDA and NO in saliva
- interventionNames
- Diagnostic Test: salivary biomarker
- label
- keratosis
- description
- MDA and NO in saliva
- interventionNames
- Diagnostic Test: salivary biomarker
- label
- leukoplakia
- description
- MDA and NO in saliva
- interventionNames
- Diagnostic Test: salivary biomarker
- label
- Oral lichen Planus
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * healthy individuals with one of the following oral lesions : * keratosis * Oral lichen planus * oral squamous cell carcinoma * oral leukoplakia Exclusion Criteria: * subjects having systemic disorders * pregnant or lactating females; * subjects who suffered from any other mucosal lesions; * severe periodontal inflammation.
References
Publications (0)
Data not yet available
No reference posted for this study.