Clinical trial · Observational
The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.
NCT04252560CI-TRIAL-00076993completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The role of gut microbiota in anastomosis insufficiency in patients operated for colorectal cancer and for peritoneal carcinomatosis is going to be investigated. This is a pilot study.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer, Peritoneal Carcinomatosis, Anastomosis Insufficiency | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Colectomy, CRS+HIPEC | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Colorectal
- description
- 30 patients operated for colorectal cancer
- interventionNames
- Procedure: Colectomy, CRS+HIPEC
- label
- HIPEC
- description
- 15 patients operated with CRS+HIPEC for peritoneal carcinomatosis
- interventionNames
- Procedure: Colectomy, CRS+HIPEC
Primary outcomes (1)
- measure
- Microbiome
- timeFrame
- 30 days
- description
- Change in microbiome in case of insufficiency of the anastomosis
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria Colorectal group * adenocarcinom in colon or rektum * curative operation planed * direct anastomose plan * elective surgery Inclusion Criteria HIPEC group : * All patients with appendix, colon or rectal cancer accepted for CRS+HIPEC Exclusion Criteria: * Ongoing antibiotics treatment * antibiotics treatment in the last 6 months * acute surgery * palliative surgery * Ulcerös colitis or Crohns disease * Prior colectomy * Small intestine stoma before the operation * neoadjuvant treatment * Colon preparation
References
Publications (0)
Data not yet available
No reference posted for this study.