Clinical trial · Interventional
Hepatocellular Carcinoma Surveillance in Cirrhotics
Increasing Surveillance Rates for Hepatocellular Carcinoma Among Cirrhotic Patients
NCT04248816CI-TRIAL-00063929completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a 3-arm pilot randomized controlled trial applying behavioral economic approaches (opt-out framing and financial incentives) to encourage patients with liver cirrhosis to complete regular surveillance ultrasounds which may allow for earlier diagnosis of and better outcomes for hepatocellular carcinoma (HCC).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cirrhosis | — | UNRESOLVED | — |
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Opt-out | Behavioral | — | UNRESOLVED |
| Opt-out + Incentive | Behavioral | — | UNRESOLVED |
| Usual care | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Usual Care
- description
- Standard of care
- interventionNames
- Behavioral: Usual care
- type
- EXPERIMENTAL
- label
- Opt-out
- description
- Facilitated outreach and opt-out framing
- interventionNames
- Behavioral: Opt-out
- type
- EXPERIMENTAL
- label
- Opt-out + Incentive
- description
- Facilitated outreach and opt-out framing plus a financial incentive
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who are 18+ years old * Current diagnosis of cirrhosis or advanced fibrosis * 1 or more visits to a Penn Gastroenterology/Hepatology practice in the preceding two years * Currently followed by Penn Gastroenterology/Hepatology * Must live in the Philadelphia Metropolitan Statistical Area Exclusion Criteria: * History of HCC or other liver carcinoma diagnosis * History of liver transplant * Completed HCC screening within the past 7 months * Have a future screening scheduled * Have a different screening modality recommended by their physician (MRI, CT, etc.) * Patients with metastatic cancer * Patients receiving hospice care
References
Publications (0)
Data not yet available
No reference posted for this study.