Clinical trial · Interventional
Effects of Early Palliative Care Integration on Patients With Newly Diagnosed Multiple Myeloma
A Pilot Study to Determine the Effects of Early Palliative Care Integration on Patients With Newly Diagnosed Multiple Myeloma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Multiple Myeloma (MM) is a common type of cancer involving the cells in the blood (commonly affecting bones, kidneys and blood). Although it remains incurable, MM has become a highly treatable form cancer thanks to new and improved treatment modalities. As patients deal with this disease, they often suffer from multiple symptoms that are caused by both the disease itself and the different drugs used to treat it. Research has shown that the most common symptoms patients suffer from include pain, constipation, tiredness, tingling in hands and feet, breathlessness, sadness and difficulty remembering things. These symptoms may negatively affect the quality of life of patients. Palliative care (PC) is a type of treatment aimed at relieving symptoms and promoting the most optimal quality of life (QOL) for patients and their caregivers. Research has shown that patients with certain types of cancers, such as colon cancer and lung cancer, do better if they are seen by a PC provider early in the course of their disease. This study seeks to determine the effects of early PC involvement on participants with newly diagnosed MM
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| FACT-MM questionnaire | Other | — | UNRESOLVED |
| HADS questionnaire | Other | — | UNRESOLVED |
| Palliative Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Early Palliative Care Integration
- description
- 12 months of PC with concurrent standard treatment for MM, QOL assessments
- interventionNames
- Other: Palliative Care
- Other: FACT-MM questionnaire
- Other: HADS questionnaire
Primary outcomes (13)
- measure
- Self-reported QOL as measured by FACT-MM scores
- timeFrame
- At baseline
- description
- Self-reported QOL as measured by FACT-MM scores The questionnaire is a combination of the original widely used and validated FACT-G (Functional Assessment of Cancer Therapy-General) questionnaire (27 items), and 14 MM-specific items. FACT-MM total scores range from 0 to 164, with FACT-G sections ranging from 0 to 108 and MM-specific section ranging from 0 to 56. Higher scores mean better QOL for all sections and total scores.
- measure
- Self-reported QOL as measured by FACT-MM scores
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Must be within eight weeks of being diagnosed with symptomatic MM based on current diagnostic criteria * Able to read and respond to questions in English * Have an ECOG performance status of 0, 1, 2 or 3 * Receiving oncologic care at a Cleveland Clinic facility Exclusion Criteria: * Have seen a PC provider in any setting (i.e., inpatient, outpatient or home-based) * Need immediate referral to PC for hospice transition
References
Publications (1)
- DERIVEDSamala RV, Nurse DP, Chen X, Wei W, Crook JJ, Fada SD, Valent J. Effects of early palliative care integration on patients with newly diagnosed multiple myeloma. Support Care Cancer. 2024 Jun 27;32(7):468. doi: 10.1007/s00520-024-08665-2. PMID 38937310