Clinical trial · Interventional
Is Thoracic Paravertebral Block a Better Option Than Conscious Sedation for PRFA of Liver Tumors
Is Thoracic Paravertebral Block a Better Option Than Conscious Sedation for Percutaneous Radiofrequency Ablation of Liver Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Percutaneus radiofrequency ablation (RFA) of liver tumors causes acute pain during the periooperative setting. In order to facilitate tumor access, patient should collaborate with a surgeon during the procedurę, therefore should be conscious. This study aims to assess the impact of a single shot thoracic paravertebral block (TPVB) on a patient's haemodynamic stability, patient's and operator's comfort and satisfaction during the operation and analgesia in the post-operative period.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Tumor | Liver Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| local anaesthesia | Procedure | — | UNRESOLVED |
| thoracic paravertebral blockade | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- group PVB
- description
- standard analgosedation + paravertebral thoracic blockade with 20 ml 0.25% bupivacaine (Bupivacainum hydrochloricum WZF 0,5%, Polfa warszawa S.A.)
- interventionNames
- Procedure: thoracic paravertebral blockade
- type
- ACTIVE_COMPARATOR
- label
- group BB
- description
- standard analgosedation + local anesthesia of the skin and subcutaneous tissue with 5ml 0,5% lignocaine (Lignocainum hydrochlorici, WZF 1%).
- interventionNames
- Procedure: local anaesthesia
Primary outcomes (2)
- measure
- Effectiveness of PVB on pain intensity
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * patients with primary liver tumor (HCC) * patient scheduled for an elective surgery * tumor diameter) \<5 cm two tumors \<3cm * Age \>18 years * Physical State 1,2 or 3 of the American Society of Anesthesiology (ASA) Exclusion Criteria: * ASA IV and V * Thrombocytopenia (\<40x10 \^ 9 / L) * Severe cirrhosis (Child-Pugh C classification) * History of psychiatric/cognitive disease * Patients who do not give informed consent * Patients with contraindications or history of hypersensitivity to local anaesthesia drugs * History of chronic pain, chronic opioid use (\> 3 months)
References
Publications (0)
Data not yet available