Clinical trial · Interventional
Well-Being After Breast Cancer Surgery
Improving Well-Being for Individuals With Persistent Pain After Surgery for Breast Cancer, Lobular Carcinoma in Situ, or Ductal Carcinoma in Situ: A Randomized Clinical Trial That Compares Three Behavioral Intervention Strategies and Examines Psychological Factors as Drivers of the Continuing Burden of Persistent Pain
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare the benefits of skills training and health education interventions designed specifically to increase the well-being of people with persistent pain after breast surgery for lobular carcinoma in situ (LCIS), ductal carcinoma in situ (DCIS), or invasive breast cancer, and to examine the roles of psychological and physiological variables as modifiable contributors to the continuing burden of persistent pain.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Coping Skills Training for Persistent Post-Surgical Pain | — | UNRESOLVED | — |
| General Health Education | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CST-PSP | Behavioral | — | UNRESOLVED |
| General health education | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Coping Skills Training for Persistent Post-Surgical Pain
- description
- novel pain coping skills training intervention designed specifically for people with persistent pain (PP) following breast cancer surgery
- interventionNames
- Behavioral: CST-PSP
- type
- ACTIVE_COMPARATOR
- label
- General health education with a coach
- description
- general health education intervention
- interventionNames
- Behavioral: General health education
- type
- ACTIVE_COMPARATOR
- label
- Self-guided health education
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * prior diagnosis of Stage 0 to III breast cancer, DCIS or LCiS * received first breast cancer surgery (total or partial mastectomy, lumpectomy) at least 3 months ago * reports score of ≥3 in the past month on the 0 to 10 breast pain severity and/or interference scale * able to speak and read English * able to provide meaningful consent Exclusion Criteria: * \<18 years of age * hearing impairment that limits use of videoconferencing for intervention sessions * cognitive impairment that is documented in the medical record or results in being unable to provide meaningful consent
References
Publications (1)
- DERIVEDStalls JM, Bovbjerg DH, Somers TJ, Plumb Vilardaga JC, Kimmick GG, McAuliffe PF, Keefe FJ, Posluszny DM, Sullivan MJL, Erkanli A, Reed SD, Sutton L, Owen L, Massa L, Shelby RA. Improving well-being for individuals with persistent pain after surgery for breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ: A randomized clinical trial. Contemp Clin Trials. 2022 Nov;122:106934. doi: 10.1016/j.cct.2022.106934. Epub 2022 Sep 21. PMID 36152791