Clinical trial · Interventional
Clinical Application of Nutrition Support Package Before Hepatectomy
Clinical Application of Preoperative Nutritional Support Package for Liver Cancer
NCT04218253CI-TRIAL-00042595unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Objective:To confirm the effect of preoperative oral nutrition therapy on patients with malnourished before liver cancer resection. Study design:Prospective, randomized, controlled clinical study. Primary end point: incidence of all complications 30 days after surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatectomy | — | UNRESOLVED | — |
| Liver Neoplasms | Liver Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Nutrition Therapy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 300 calories or 500 calories nutrient rich in branched chain amino acids and dietary fiber | Dietary Supplement | — | UNRESOLVED |
| Dietary mission | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- nutritional intervention
- description
- 300 or 500 calories nutritional support before operation according to the level of malnutrition
- interventionNames
- Dietary Supplement: 300 calories or 500 calories nutrient rich in branched chain amino acids and dietary fiber
- Behavioral: Dietary mission
- type
- OTHER
- label
- control group
- description
- Dietary education was conducted according to preoperative nutritional requirements
- interventionNames
- Behavioral: Dietary mission
Primary outcomes (1)
- measure
- Incidence of complications at 30 days after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * 1\. Clinical diagnosis of primary liver cancer (including hepatocellular carcinoma, bile duct carcinoma, and mixed cell carcinoma) * 2\. No contraindications for surgery * 3\. Eastern Cooperative Oncology Group (ECOG) score of preoperative physical state \<2 points * 4\. Preoperative liver function score Child-Pugh ≤ 6 points: total bilirubin ≤ 3.0 mg / dl, albumin ≥ 28 g / L, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) ≤ 5 times the upper limit of normal * 5\. Voluntarily enter the study and sign the informed consent form, and communicate well with the researcher Exclusion Criteria: * 1\. Patients who took fish oil supplements within 3 weeks before the study began * 2\. Patients with severe nutritional risk: serious nutritional risk should be considered when combining any of the following conditions: weight loss \> 10% within 6 months; digital pain score (NRS) score \> 5 points; BMI \<18.5 kg/m2 (all patients with severe nutritional risk undergo individualized supportive care); * 3\. Patients with malignant tumors in other parts * 4\. Patients who are pregnant or lactating * 5\. Patients with mental and neurological disorders who cannot cooperate with medical staff * 6\. Patients with severe diabetes or poor glycemic control * 7\. Patients cannot tolerate nutritional preparations * 8\. Other circumstances that the researcher considers inappropriate to participate in the study
References
Publications (0)
Data not yet available
No reference posted for this study.