Clinical trial · Observational
Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management
Utilization of the Natural History of Medullary Thyroid Carcinoma to Inform Advanced Disease Management
NCT04216732CI-TRIAL-00104720recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
This study utilizes a multi-institutional registry to describe the natural history of medullary thyroid cancer that has spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) in understanding disease management. The goal of this study is to learn about how medullary thyroid cancer develops and progresses.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Thyroid Gland Medullary Carcinoma | Thyroid Gland Medullary Carcinoma | CURATED_BROADER | 0.78 |
| Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Thyroid Gland Medullary Carcinoma | CURATED_BROADER | 0.78 |
| Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8 | Thyroid Gland Medullary Carcinoma | CURATED_BROADER | 0.78 |
| Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8 | Thyroid Gland Medullary Carcinoma | CURATED_BROADER | 0.78 |
| Stage IVC Thyroid Gland Medullary Carcinoma AJCC v8 | Thyroid Gland Medullary Carcinoma | CURATED_BROADER | 0.78 |
| Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Thyroid Gland Medullary Carcinoma | CURATED_BROADER | 0.78 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood Pressure Measurement | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational (questionnaire, blood pressure)
- description
- AIM I \& II: Patients complete questionnaires over 10-40 minutes 2-4 times per year about health and how finances and quality of life effect experience with disease. AIM III: Patients complete a questionnaire over 2 minutes and undergo blood pressure measurements every day for up to 12 weeks.
- interventionNames
- Other: Blood Pressure Measurement
- Other: Questionnaire Administration
Primary outcomes (3)
- measure
- Natural history of medullary thyroid cancer (MTC)
- timeFrame
- Up to 4 years
- description
- Will describe the natural history of MTC using comprehensive battery of demographic, clinical, pathologic, and genotypic variables collected in existing multi-institutional patient registry.
- measure
- Patients' experience with the different phases of MTC
- timeFrame
- Up to 4 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Aims 1 and 2: A diagnosis of MTC * Aims 1 and 2: A registrant in the Medullary Thyroid Cancer Registry (MTCR). Patients of all disease phases will be eligible for enrollment * Aim 3: A diagnosis of advanced phase (red or gray) MTC as determined by clinical team * Aim 3: A current registrant in the MTCR
References
Publications (0)
Data not yet available
No reference posted for this study.