Clinical trial · Observational
Effect of Radiation Therapy Among Head and Neck Cancer Patients on the Inner Ear Function
Evaluation of the Effect of Radiation Therapy Among Head and Neck Cancer Patients on the Inner Ear Function Using Novel Techniques
NCT04214769CI-TRIAL-00042567unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aims: 1. To evaluate the effects of radiation therapy on the inner ear, among patients treated with radiation therapy for head and neck cancers using a wide battery of tests (Audiometry and tympanometry, vHIT, VEMP, ENG) ; 2. To correlate the mean total radiation dose to the cochlea with the effects on audiological and vestibular function
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer Patients Treated With Radiotherapy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Audiometry and tympanometry, vHIT, VEMP, ENG | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Head and Neck Cancer patients
- interventionNames
- Diagnostic Test: Audiometry and tympanometry, vHIT, VEMP, ENG
Primary outcomes (4)
- measure
- Audiometry
- timeFrame
- 1.5 Year
- description
- The change in hearing threshold and in the speech-audiometry
- measure
- ENG test
- timeFrame
- 1.5 Year
- description
- Abnormal function of the central vestibular pathways, unilateral weakness of the vestibular apparatus or direction preponderance
- measure
- VEMP test
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Females and males, Age: ≥ 18 years old * Patients diagnosed Head and Neck cancers, not treated previously * Planned for radiation therapy in which the inner ear will be radiated Exclusion Criteria: * Patients who were previously diagnosed with a vestibular disorder * Previous middle or inner ear anomaly * Failure to complete the whole course of radiation therapy * More than one course of radiation therapy * Patients treated with concurrent ototoxic chemotherapy * Pregnant women * Patients who will not sign an informed consent form * Helpless or incompetent patients
References
Publications (0)
Data not yet available
No reference posted for this study.