Clinical trial · Observational
EsophaCap for the Detection of Early Esophageal Carcinoma
NCT04214119CI-TRIAL-00099057recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Barrett Esophagus | — | UNRESOLVED | — |
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (4)
- label
- Control
- description
- Patients age 18 or greater who have undergone esophagogastroduodenoscopy and does not have a diagnosis of Barrett's esophagus or esophageal/gastric malignancy.
- label
- Barrett's esophagus
- description
- Patients age 18 or greater who have undergone esophagogastroduodenoscopy and diagnosed with Barrett's esophagus via pathology.
- label
- Esophageal carcinoma
- description
- Patients age 18 or greater who have diagnosis of primary esophageal carcinoma.
- label
- Gastric cancer
- description
- Patients age 18 or greater who have diagnosis of primary esophageal cancer.
Primary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Undergoing esophagogastroduodenoscopy at Johns Hopkins Hospital from 1/2016 to 12/2025 * Age greater than 18 years * Patients must be able to swallow a capsule Exclusion Criteria: * Patients in either arm with extra-esophageal malignancies including head and neck and gastric cancer * Patients who have undergone esophagectomy * Patients who have undergone radiation to the chest * Patients who are younger than 18 * Patients with esophageal stents * Patients with esophageal strictures disabling passage of the capsule
References
Publications (0)
Data not yet available
No reference posted for this study.