Clinical trial · Observational
A Pilot Study to Explore the Role of Gut Flora in Metastatic Mesothelioma
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Metastatic Mesothelioma
NCT04214015CI-TRIAL-00090606withdrawnClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Company focus shifted
Summary
Brief summary (as posted)
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mesothelioma | Malignant Mesothelioma | CURATED_EXACT | 0.92 |
| Mesothelioma; Liver | — | UNRESOLVED | — |
| Mesothelioma; Lung | — | UNRESOLVED | — |
| Mesothelioma Malignant | Malignant Mesothelioma | ALIAS | 0.90 |
| Mesothelioma; Omentum | — | UNRESOLVED | — |
| Mesothelioma Peritoneum | — | UNRESOLVED | — |
| Mesotheliomas Pleural | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with metastatic mesothelioma
- description
- Patients who have been diagnosed with metastatic mesothelioma
- interventionNames
- Other: No intervention
Primary outcomes (1)
- measure
- Correlation of Microbiome to Disease via Relative Abundance Found in Microbiome Sequencing
- timeFrame
- Three years
- description
- Relative abundance of bacterial classes within taxonomic phyla and, more broadly, within their domain will be analyzed by sequencing the gut microbiome. These data will then be categorized with metastatic mesothelioma
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study a. May be signed by parent or legal guardian in the case of minor or adult unable to provide consent 2. Male or female of all ages. (interest is given to children who present with autism or Crohn's and whose parents wish to analyze their children's gut flora. Also of interest analysis of development of the child's microbiome. In the case of autism, the younger the child, the better to correct the neurological problems if an association is found between autism and the microbiome) 3. Diagnosis of metastatic mesothelioma through biopsy and/or advanced imaging Exclusion Criteria: 1. Refusal to sign informed consent form 2. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy. 3. Postoperative stoma, ostomy, or ileoanal pouch 4. Participation in any experimental drug protocol within the past 12 weeks 5. Treatment with total parenteral nutrition
References
Publications (0)
Data not yet available
No reference posted for this study.