Clinical trial · Observational
Laparoscopic Partial Nephrectomy for cT1 Tumors
Evaluation Trifecta and Pentafecta Outcomes of Patients Underwent Laparoscopic Partial Nephrectomy for cT1 Renal Tumor
NCT04213157CI-TRIAL-00042543completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the study is to evaluate trifecta and pentafecta outcomes for laparoscopic partial nephrectomy (LNP) in patients with clinical T1N0M0 renal tumor.
Conditions
Conditions (13)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Kidney Injury | — | UNRESOLVED | — |
| Kidney Ischemia | — | UNRESOLVED | — |
| Kidney Neoplasms | Kidney Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Oncology | — | UNRESOLVED | — |
| Oncology Problem | — | UNRESOLVED | — |
| Renal Cancer | — | UNRESOLVED | — |
| Renal Cell Carcinoma | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
| Renal Functional Abnormality | — | UNRESOLVED | — |
| Renal Neoplasm | Kidney Neoplasm | ALIAS | 0.90 |
| Surgery | — | UNRESOLVED | — |
| Surgery--Complications | — | UNRESOLVED |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (10)
- measure
- Operation time
- timeFrame
- at the end of the surgery
- description
- time from onset to complete of surgery
- measure
- Blood loss
- timeFrame
- at the end of the surgery
- description
- amount of bleeding during surgery (mL)
- measure
- warm ischemia time
- timeFrame
- at the and of the surgery
- description
- The clamp time of the renal artery and vein which is required to complete tumor excision and renorrhaphy
- measure
- intraoperative complication
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 82 Years
Show eligibility criteria text
Inclusion Criteria: * Functioning contraleteral kidney * Patients with complete data * Patients with single renal tumor on the effected side * Patients who approved the written consent form Exclusion Criteria: * The patients with bilateral renal tumors (n=8, 16 LPNs) * solitary kidney (n=8) * horseshoe kidney (n=4) * pelvic ectopic kidney (n=2) * graft kidney (n=2) * those with multiple renal tumors in a single kidney (n=3) or with \> 7 cm renal tumor (n=6) * Patients who were operated on for colon cancer (n=4), prostate cancer (n=2), endometrial cancer (n=1) or adrenal mass (n=2) within the first year after LPN
References
Publications (5)
- RESULTPorpiglia F, Bertolo R, Amparore D, Fiori C. Margins, ischaemia and complications rate after laparoscopic partial nephrectomy: impact of learning curve and tumour anatomical characteristics. BJU Int. 2013 Dec;112(8):1125-32. doi: 10.1111/bju.12317. Epub 2013 Aug 13. PMID 23937616
- RESULTMinervini A, Siena G, Antonelli A, Bianchi G, Bocciardi AM, Cosciani Cunico S, Ficarra V, Fiori C, Fusco F, Mari A, Martorana G, Medica M, Mirone V, Morgia G, Porpiglia F, Rocco F, Rovereto B, Schiavina R, Simeone C, Terrone C, Volpe A, Carini M, Serni S; Members of the RECORd Project-LUNA Foundation. Open versus laparoscopic partial nephrectomy for clinical T1a renal masses: a matched-pair comparison of 280 patients with TRIFECTA outcomes (RECORd Project). World J Urol. 2014 Feb;32(1):257-63. doi: 10.1007/s00345-013-1155-7. Epub 2013 Sep 7. PMID 24013181
- RESULTOsaka K, Makiyama K, Nakaigawa N, Yao M. Predictors of trifecta outcomes in laparoscopic partial nephrectomy for clinical T1a renal masses. Int J Urol. 2015 Nov;22(11):1000-5. doi: 10.1111/iju.12893. Epub 2015 Aug 6. PMID 26251228
- RESULTRais-Bahrami S, Romero FR, Lima GC, Kohanim S, Permpongkosol S, Trock BJ, Jarrett TW, Kavoussi LR. Elective laparoscopic partial nephrectomy in patients with tumors >4 cm. Urology. 2008 Sep;72(3):580-3. doi: 10.1016/j.urology.2008.05.027. Epub 2008 Jul 16. PMID 18632142
- DERIVEDMercimek MN, Ozden E, Gulsen M, Yakupoglu YK, Bostanci Y, Sarikaya S. Which Is the Best Predictor to Achieve Trifecta in Patients Undergoing Elective Laparoscopic Partial Nephrectomy with Global Hilar Clamping? Comparative Analysis in Patients with Clinical T1a and T1b Renal Tumors. J Endourol. 2021 May;35(5):615-622. doi: 10.1089/end.2020.0758. Epub 2020 Nov 5. PMID 32967451