Clinical trial · Interventional
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma
Amplification of Zinc- Finger Protein 217 Gene in Multiple Myeloma Patients as a Prognostic Marker
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Multiple myeloma (MM) is blood disorder characterized by the detection of a monoclonal paraprotein in serum or urine, which is often associated with the presence of clonal plasma cells (PCs) mainly in the bone marrow (BM) .The zinc-finger protein 217 (ZNF217) is an oncogenic protein that plays deleterious functions in various human cancers. The ZNF217 gene is located at the 20q13 chromosomal region, which is frequently amplified in human tumors .
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| zinc-finger protein 217 gene | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- case
- description
- myeloma patients
- interventionNames
- Genetic: zinc-finger protein 217 gene
- type
- EXPERIMENTAL
- label
- control
- description
- healthy control
- interventionNames
- Genetic: zinc-finger protein 217 gene
Primary outcomes (1)
- measure
- zinc-finger protein gene 217 in myeloma patients
- timeFrame
- 2 years
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Newly diagnosed multiple myeloma patients, who fulfill the WHO criteria of myeloma diagnosis. Exclusion Criteria: * Patients with any other type of malignant or benign tumors should be excluded from our study.
References
Publications (0)
Data not yet available