Clinical trial · Observational
To Explore the Related Factors of Cough After Thoracoscopic Pneumonectomy
Multivariate Analysis of Cough After Uniport Video-assisted Thoracoscopic Surgery Pneumonectomy
NCT04204148CI-TRIAL-00042404unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To explore the related factors of cough after Uniport video-assisted thoracoscopic surgery pneumonectomy, and to provide theoretical basis and social accumulation of new knowledge for the diagnosis and treatment of cough after pneumonectomy in the future.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cough | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Clinical characteristics of the patients
- description
- including sex,age,smoking history,tumor location and tumor diameter
- label
- Logistic regression analysis of influencing factors of c
- description
- The Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC) was used to evaluate the degree of cough in patients. The LCQ-MC is divided into three dimensions: physical, psychological and social. There are a total of 19 questions, and each question has seven options (positive scoring, grades 1-7; the higher the score is, the lighter the cough).
Primary outcomes (1)
- measure
- The mean Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC) score before and after surgery
- timeFrame
- The day before surgery,two weeks after surgery,one month after surgery
- description
- The Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC), which assesses the cough-related quality of life, consists of 19 items divided into three domains: the physical (8 items), psychological (7 items) and social (4 items) domains. A 7-point Likert scale was used to score individual domains. The total scores ranged from 3 to 21, with a higher score indicative of a better health status
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 years old, male and female * Uniport video-assisted thoracoscopic surgery * No cough symptoms within two weeks before operation * Informed consent form was signed before operation Exclusion Criteria: * Diabetes , heart, brain, liver and kidney diseases * Chest radiographs / CT in recent months indicate pneumonia * Pulmonary function cannot tolerate lobectomy / segmental / cuneiform resection * Distant metastasis patients * Before operation, there were internal causes of cough (including respiratory tract infectious diseases, pharyngitis, allergic rhinitis, posterior nasal drip syndrome, etc.)
References
Publications (8)
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- RESULTBirring SS, Spinou A. How best to measure cough clinically. Curr Opin Pharmacol. 2015 Jun;22:37-40. doi: 10.1016/j.coph.2015.03.003. Epub 2015 Mar 25. PMID 25819594
- RESULTHarle ASM, Blackhall FH, Molassiotis A, Yorke J, Dockry R, Holt KJ, Yuill D, Baker K, Smith JA. Cough in Patients With Lung Cancer: A Longitudinal Observational Study of Characterization and Clinical Associations. Chest. 2019 Jan;155(1):103-113. doi: 10.1016/j.chest.2018.10.003. Epub 2018 Oct 13. PMID 30321508
- RESULTBrignall K, Jayaraman B, Birring SS. Quality of life and psychosocial aspects of cough. Lung. 2008;186 Suppl 1:S55-8. doi: 10.1007/s00408-007-9034-x. Epub 2007 Oct 16. PMID 17939003
- RESULTXie MR, Zhu YF, Zhou MQ, Wu SB, Xu GW, Xu SB, Xu MQ. Analysis of factors related to chronic cough after lung cancer surgery. Thorac Cancer. 2019 Apr;10(4):898-903. doi: 10.1111/1759-7714.13021. Epub 2019 Mar 15. PMID 30875149
- RESULTKoskela HO, Latti AM, Pekkanen J. The impacts of cough: a cross-sectional study in a Finnish adult employee population. ERJ Open Res. 2018 Nov 12;4(4):00113-2018. doi: 10.1183/23120541.00113-2018. eCollection 2018 Oct. PMID 30443552
- RESULTWang P, Zhu M, Zhang D, Guo XG, Zhao S, Zhang XL, Wang DL, Liu CT. The relationship between chronic obstructive pulmonary disease and non-small cell lung cancer in the elderly. Cancer Med. 2019 Aug;8(9):4124-4134. doi: 10.1002/cam4.2333. Epub 2019 Jun 11. PMID 31184445
- DERIVEDPan LY, Peng LP, Xu C, Ding C, Chen J, Wang WY, Zhu XY, Zhao J, Li C. Predictive factors of cough after uniportal video-assisted thoracoscopic pulmonary resection. J Thorac Dis. 2020 Oct;12(10):5958-5969. doi: 10.21037/jtd-20-2652.