Clinical trial · Observational
Apple Women's Health Study
NCT04196595CI-TRIAL-00078501recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research app(available on App Store), which allows a user to find, enroll, and participate in Apple-supported health-related research studies.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Infertility | — | UNRESOLVED | — |
| Menopause | — | UNRESOLVED | — |
| Menstrual Cycle | — | UNRESOLVED | — |
| Menstruation | — | UNRESOLVED | — |
| Ovulation | — | UNRESOLVED | — |
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
| Reproduction | — | UNRESOLVED | — |
| Reproductive Health | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Identify Menstrual Cycle Patterns
- timeFrame
- Up to 10 years
- description
- Characterized using duration of menstrual flow, and cycle length in unit of days.
- measure
- Epidemiologic Description of Menstrual Cycle
- timeFrame
- Up to 10 years
- description
- Characterized using cycle patterns and self-reported demographics, no unit of measure
Secondary outcomes (1)
- measure
- Determine prevalence of gynecologic health conditions
- timeFrame
- Up to 10 years
- description
- Characterized using menstrual cycle patterns and self-reported health conditions, no unit of measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Have menstruated at least once * Be at least 18 years old (at least 19 years old in Alabama and Nebraska, at least 21 years old in Puerto Rico) * Live in the United States of America * Be comfortable communicating in written and spoken English * Have installed the Apple Research app on your iPhone * Not share your iCloud account or iPhone with anyone else * Be willing and able to provide informed consent to participate in the study
References
Publications (2)
- DERIVEDWang Z, Peebles E, Baird DD, Jukic AMZ, Wilcox AJ, Curry CL, Fischer-Colbrie T, Onnela JP, Williams MA, Hauser R, Coull BA, Mahalingaiah S. Menstrual product use patterns in a large digital cohort in the United States: variations by sociodemographic, health, and menstrual characteristics. Am J Obstet Gynecol. 2025 Sep;233(3):184.e1-184.e15. doi: 10.1016/j.ajog.2025.03.002. Epub 2025 Mar 10. PMID 40073916
- DERIVEDZhang CY, Li H, Zhang S, Suharwardy S, Chaturvedi U, Fischer-Colbrie T, Maratta LA, Onnela JP, Coull BA, Hauser R, Williams MA, Baird DD, Jukic AMZ, Mahalingaiah S, Curry CL. Abnormal uterine bleeding patterns determined through menstrual tracking among participants in the Apple Women's Health Study. Am J Obstet Gynecol. 2023 Feb;228(2):213.e1-213.e22. doi: 10.1016/j.ajog.2022.10.029. Epub 2022 Oct 29. PMID 36414993