Clinical trial · Interventional
High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Inflammatory Bowel Disease (IBD) involving the colon is a known risk for colon cancer. There are two standards-of-care colonoscopy techniques used for screening all patients who suffer from IBD for more than eight years. One method is to obtain random biopsies throughout the colon and the other is by using dye spraying chromo-colonoscopy. This trial aims to study the difference between the two colonoscopy techniques during the era of high definition camera in detecting neoplastic lesions during screening patients with long-standing IBD.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Dysplasia | — | UNRESOLVED | — |
| Crohn Colitis | — | UNRESOLVED | — |
| Indeterminate Colitis | — | UNRESOLVED | — |
| Inflammatory Bowel Diseases | — | UNRESOLVED | — |
| Ulcerative Colitis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dye Spraying Chromocolonoscopy | Device | — | UNRESOLVED |
| High Definition Colonoscopy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- High Definition White Light Colonoscopy
- interventionNames
- Device: High Definition Colonoscopy
- type
- ACTIVE_COMPARATOR
- label
- Dye Spraying Chromo-colonoscopy
- interventionNames
- Device: Dye Spraying Chromocolonoscopy
Primary outcomes (1)
- measure
- Detection rate of dysplastic lesions in High Definition White Light Colonoscopy versus Dye Spraying Chromo-colonoscopy
- timeFrame
- Immediately after the procedure
Secondary outcomes (7)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patient age ≥18yr old 2. History of UC or colonic Crohn's disease or unclassified colitis patients with or without colonic adenoma history 3. Duration of ≥ eight years since diagnosis, or any duration with a diagnosis of primary sclerosing cholangitis 4. Mucosal lesion involves ≥ 1/3 of the colon Exclusion Criteria: 1. History of colorectal cancer 2. History of total colectomy 3. Prior colonoscopy within the last 6 months 4. Allergy to dye spray 5. Poor bowel preparation 6. Unable to provide informed consent 7. Severe inflammation preventing visualization of the mucosa during the procedure.
References
Publications (0)
Data not yet available