Clinical trial · Interventional
Effects of a Traditional Chinese Exercise Program on Symptom Cluster in Breast Cancer Patients
Effects of a Traditional Chinese Exercise Program- Tai Chi on Symptom Cluster of Fatigue-sleep Disturbance-depression in Female Breast Cancer Patients: a Preliminary Randomized Controlled Trial
NCT04190342CI-TRIAL-00057348completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Medical Research Council Framework for Developing and Evaluating Complex Interventions (MRC Framework) will be utilized to develop and evaluate an evidence-based tai chi intervention for managing the symptom cluster of fatigue-sleep disturbance-depression in breast cancer patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasm Female | — | UNRESOLVED | — |
| Symptom Cluster | — | UNRESOLVED | — |
| Tai ji | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| control group | Other | — | UNRESOLVED |
| tai chi group | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- control group
- description
- standard care (intervention provided after the completion of the trial)
- interventionNames
- Other: control group
- type
- EXPERIMENTAL
- label
- tai chi group
- description
- Tai chi intervention + standard care
- interventionNames
- Behavioral: tai chi group
Primary outcomes (11)
- measure
- Time taken to recruit planned sample
- timeFrame
- From baseline (T1) to the completion of the 8-week intervention (T2)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Female, aged 18 years old or above; 2. a confirmed diagnosis of non-metastatic stage I, II, or IIIa BC; 3. have experienced at least a moderate level of tiredness, sleep disturbance, and depressive mood, with a score of greater than 3 on a 10-point numeric rating scale, from "0 (no symptom)" to "10 (worst symptom)" for each symptom in the previous one month; 4. have recently commenced adjuvant chemotherapy; and 5. able to follow instructions in Mandarin, interested in participating in the study, and willing to sign an informed consent. Exclusion Criteria: 1. Currently using psychostimulants, antidepressant medications, or hypnotics medications; 2. extremely weak or have mental illness and/or intellectual disability; 3. have been involved in other exercise programs \> 30 minutes, three times weekly, for past 3 months; 4. have practised tai chi for the past six months; and 5. have scheduled elective surgery during the study period.
References
Publications (1)
- DERIVEDYao LQ, Tan JB, Turner C, Wang T. Feasibility and potential effects of tai chi for the fatigue-sleep disturbance-depression symptom cluster in patients with breast cancer: protocol of a preliminary randomised controlled trial. BMJ Open. 2021 Aug 18;11(8):e048115. doi: 10.1136/bmjopen-2020-048115. PMID 34408044