Clinical trial · Interventional
Butyrophilins Role in Colon Cancer
Role of Butyrophilins in Colon Cancers Aggressiveness Evaluation
NCT04185272CI-TRIAL-00091020recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
quantification of BTNL molecules in colon cancer in order to determinate if their could be used as a prognostic marquer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Cancer | Colon Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| analysis of BTN and BTNL status | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- non-metastatic colon cancer
- interventionNames
- Biological: analysis of BTN and BTNL status
- type
- EXPERIMENTAL
- label
- metastatic colon cancer
- interventionNames
- Biological: analysis of BTN and BTNL status
Primary outcomes (1)
- measure
- evaluation of BTNL3, BTNL8 and BTNL9 expression by transcriptomics and immunohistochemistry
- timeFrame
- 8 years
- description
- healthy and cancerous colon ad metastasis (if applicable) will be analysed by
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient is older than 18 years old, * Signed participation consent, * Non-metastatic colon cancer immediately resectable or metastatic and liver synchronous for which it was decided a combined colic and liver surgery (metastatic patient at the outset) in multidisciplinary consultation meeting. * Performance Status (PS) 0 or 1 * affiliated to the social security or beneficiary Exclusion Criteria: * Rectal cancer, colon cancer recurrence * Emergency of colon cancer Surgery * History of inflammatory disease of the digestive tract (Crohn's disease or ulcerative colitis) * Patient who received neoadjuvant therapy other than chemotherapy * Patient treated with immune-suppressors or long-course corticosteroids \<12 months * Pregnant women or likely to be pregnant (without effective contraception) or breastfeeding, * Person in urgent situation, person under legal protection measure, or unable to express his / her consent, * Impossibility of submitting to the medical examination of the test for geographical, social or psychological reasons
References
Publications (0)
Data not yet available
No reference posted for this study.