Clinical trial · Observational
AG & IM in CA Stomach Protocol
Performance of Endoscopic and Histological Criteria of Atrophic Gastritis and Intestinal Metaplasia in Predicting Risk of Gastric Cancer - a Multicenter Case Control Study
NCT04184960CI-TRIAL-00069379unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a multi-center prospective case control study aiming to compare different methods of risk stratification models in predicting the risk of gastric cancer development.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Atrophic Gastritis | — | UNRESOLVED | — |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Intestinal Metaplasia | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gastroscopy and gastric biopsies | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Gastric cancer cohort
- description
- Cohort of patients with gastric cancer
- interventionNames
- Diagnostic Test: Gastroscopy and gastric biopsies
- label
- Non-gastric cancer cohort
- description
- Cohort of patients without gastric cancer
- interventionNames
- Diagnostic Test: Gastroscopy and gastric biopsies
Primary outcomes (5)
- measure
- Endoscopic grading of atrophic gastritis (Kimura Takemoto Classification)
- timeFrame
- Cross sectional study, day 0
- description
- Endoscopic description of severity of gastric atrophy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
Show eligibility criteria text
Two groups of patients would be recruited in this case control study. 1. Gastric neoplasia group Patients with newly diagnosed or history of cancer of stomach or gastric high grade dysplasia. 2. Control group Patients with no prior history of gastric dysplasia or cancer Inclusion criteria: 1. Age 40 or above 2. Undergo elective upper gastrointestinal endoscopy Exclusion criteria: 1. Patients with history of gastrectomy 2. Patients with severe thrombocytopenia (Platelet count \<50) or coagulopathy (INR \> 1.5 or on anticoagulation) 3. Contraindication to upper gastrointestinal endoscopy 4. Allergy towards sedative agents (Midazolam / Diazepam) or local anaesthetic spray (Lignocaine) 5. Patients who cannot give informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.