Clinical trial · Observational
Hypermethylation of VTRNA2-1 Promoter in HCC Outcome
Differential Hypermethylation Status of the VTRNA2-1 Promoter in Hepatocellular Carcinoma as an Independent Factor After Partial Hepatectomy
NCT04177316CI-TRIAL-00041921completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The clinic-pathological data were retrieved from the cancer registry database from the Cancer Center of Chang Gung Memorial Hospital, Linkou branch. Of the 92 HCC patients with partial hepatectomies enrolled. The biological specimen was studied with approval.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma Resectable | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- hypermethylation
- description
- The hypermethylation group was defined as differential methylation status of tumor- normal ≥ 5%.
- label
- hypomethylation/no change
- description
- The hypomethylation were defined as differential methylation status of tumor- normal \<5%
Primary outcomes (1)
- measure
- disease free survival (DFS)
- timeFrame
- a month
- description
- The length of time from curative hepatectomies treatment and recurrence or mortality
Secondary outcomes (1)
- measure
- Overall survival
- timeFrame
- a month
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: subjects with pathologic diagnosis of hepatocellular carcinoma curative partial hepatectomies Exclusion Criteria: history of different malignant disease. subjects cannot be treated with curative surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.