Clinical trial · Observational
Evaluation of Thiol Disulfide Balance in Stage 1 Endometrium Cancer
Assessment of Thiol Disulfide Balance in Early Stage Endometrium Cancer
NCT04175067CI-TRIAL-00041863completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to investigate thiol-disulfide balance in early stage endometrium cancer patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrium Cancer | Endometrial Neoplasm | PROBABILISTIC | 0.70 |
| Oxidative Stress | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Disulphide(μmol/L) | Diagnostic Test | — | UNRESOLVED |
| Total Oxidant Capacity(μmolH2O2Equiv/L) | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Endometrium cancer
- description
- stage I endometrium cancer n=57
- interventionNames
- Diagnostic Test: Disulphide(μmol/L)
- Diagnostic Test: Total Oxidant Capacity(μmolH2O2Equiv/L)
- label
- Healthy controls
- description
- Healthy volunteers n=60
- interventionNames
- Diagnostic Test: Disulphide(μmol/L)
- Diagnostic Test: Total Oxidant Capacity(μmolH2O2Equiv/L)
Primary outcomes (6)
- measure
- serum native thiol level
- timeFrame
- preoperative in the morning or preprandial for healthy volunteers
- description
- serum native thiol level in μmol/L
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: • Histopathologically confirmed diagnosis of stage I endometrium cancer Exclusion Criteria: * pulmonary disease * pulmonary hypertension * cardiac dysfunction * renal dysfunction * liver disease * chronic ishemia * systemic inflammation * concomitant malignancy * patients who use vitamin A,C or E (antioxidant vitamins) * patients who use smoke * patients who use drink alcohol * patients who use addictive for any drug
References
Publications (0)
Data not yet available
No reference posted for this study.