Clinical trial · Interventional
Multimodal Intervention for Patients With Non-small Cell Lung Cancer
Multimodal Intervention (Dietary Counselling, Fish Oil and Physical Training) for Patients With Non-small Cell Lung Cancer, a Feasibility Study
NCT04161794CI-TRIAL-00041599completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A single-arm intervention study assessing the feasibility of a multimodal intervention of management of cancer cachexia in patients with non-small cell lung cancer during primary anti-neoplastic treatment. The effects of the intervention is compared to a historical control group
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cachexia; Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| multimodal | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention group
- description
- 2 g EPA/DHA via fish oil daily Regular dietary counselling Twice weekly strength and cardiovascular exercise
- interventionNames
- Other: multimodal
- type
- NO_INTERVENTION
- label
- Historical control group
- description
- Standard of Care
Primary outcomes (3)
- measure
- Feasibility, recruitment rate
- timeFrame
- 9 months
- description
- Recruitment rate is measured by dividing the number of patients consented by the number of patients screened
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * histopathologically or cytologically verified with NSCLC * inoperable tumour, candidates for, but naïve to or no systemic anti-neoplastic treatment the previous two years * commence first line of chemotherapy (carboplatin/vinorelbin, cisplatin/vinorelbin) with or without radiation therapy or pembrolizumab * performance status ≤2 (Eastern Cooperative Oncology Group) * age \>18 and provided oral * written consent Exclusion Criteria: * excessive alcohol or drug abuse * incapable to follow the intervention (i.e. cognitive problems or unable to walk) were excluded.
References
Publications (1)
- DERIVEDTobberup R, Carus A, Rasmussen HH, Falkmer UG, Jorgensen MG, Schmidt EB, Jensen NA, Mark EB, Delekta AM, Antoniussen CS, Bogsted M, Holst M. Feasibility of a multimodal intervention on malnutrition in patients with lung cancer during primary anti-neoplastic treatment. Clin Nutr. 2021 Feb;40(2):525-533. doi: 10.1016/j.clnu.2020.05.050. Epub 2020 Jun 9. PMID 32600857