Clinical trial · Observational
A Real World Study of Laparoscopic Preservation of the Pylorus Gastrectomy
A Real World Study of the Effect of Laparoscopic Preservation of the Pylorus and Vagus Nerve on the Postoperative Quality of Life in Patients With Early Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
For the patients with early gastric cancer (T1), preoperative evaluation (gastroscope, ultrasound gastroscope and abdominal enhanced CT) showed that the tumor was located in the body of the stomach, and the margin was enough to retain the pylorus and non lymph node metastasis (N0). Lappg (D1 + lymph node dissection) and traditional laparoscopic distal gastrectomy (BII type anastomosis, D1 + lymph node dissection) were included A control study was conducted to evaluate the difference of long-term quality of life, gastric emptying rate, incidence of basic reflux gastritis, bile contraction function, immune index, nutritional index and disease-free survival and overall survival between the two groups.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| lappg | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- lappg
- interventionNames
- Procedure: lappg
- label
- ladgbi
- interventionNames
- Procedure: lappg
Primary outcomes (1)
- measure
- EORTC Questionnaire QLQ-C30
- timeFrame
- 5 years
- description
- Among the multiple tools to evaluate QOL of postgastrectomy patients, the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire QLQ-C30 have been used most extensively.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1\) 18 years old \< age \< 75 years old; (2) primary gastric lesions were diagnosed as gastric adenocarcinoma by biopsy; (3) the preoperative clinical stage was T1N0M0 according to ajcc-7thtnm; (4) it is predicted that R0 can be obtained by pylorogastric gastrectomy and D1 + lymph node dissection; (5) preoperative ECoG physical state score 0 / 1; (6) preoperative ASA score I-III; (7) informed consent of patients. Exclusion Criteria: 1. pregnant or lactating women; suffering from serious mental illness; 2. the history of upper abdominal surgery (except laparoscopic cholecystectomy); 3. history of gastric surgery (including ESD / EMR for gastric cancer); 4. preoperative imaging examination showed regional enlarged lymph nodes; 5. having other malignant diseases within 5 years; 6. patients with gastric cancer who have received new adjuvant therapy or recommended new adjuvant therapy; 7. there was a history of unstable angina or myocardial infarction within 6 months; 8. have a history of cerebral infarction or cerebral hemorrhage within 6 months; 9. there was a history of continuous systemic corticosteroid therapy within 1 month; 10. simultaneous surgical treatment of other diseases is needed; 11. gastric cancer with complications (hemorrhage, perforation, obstruction) requires emergency surgery; 12. FEV1 of pulmonary function examination was less than 50% of the predicted value.
References
Publications (0)
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