Clinical trial · Observational
Prevalence and Spectrum of Cancer Susceptibility Among Patients with Advanced Colorectal Polyps
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients with Advanced Colorectal Polyps
NCT04160832CI-TRIAL-00084709completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study is being conducted to determine the prevalence and risk factors for germline cancer susceptibility genetic mutations among patients with advanced colorectal polyps.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasm | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Multi-Cancer Cancer Panel | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Prevalence of germline pathogenic/likely pathogenic variants in cancer predisposition genes in patients with advanced colorectal polyps
- timeFrame
- 3 years
Secondary outcomes (1)
- measure
- Risk factors for germline pathogenic/likely pathogenic variants in patients with advanced colorectal polyps
- timeFrame
- 3 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 89 Years
Show eligibility criteria text
Inclusion Criteria: * Provision to sign and date the consent form * Stated willingness to comply with all study procedures and be available for the duration of the study * Be a male or female aged 18-89 * Undergone colonoscopy * At least one advanced colorectal polyp, defined as having any of the following: * Any polyp ≥ 1cm (adenoma or serrated polyp) * Any polyp with villous architecture * Any polyp with high-grade dysplasia * Sessile serrated polyps with any dysplasia * Traditional serrated adenoma Exclusion Criteria: * Known hereditary cancer syndrome * Personal history of inflammatory bowel disease * Personal history of colorectal cancer * Polyp histology or size unavailable or not documented
References
Publications (0)
Data not yet available
No reference posted for this study.