Clinical trial · Observational
Construction and Evaluation of the Liquid Biopsy-based Early Diagnostic Model for Lung Cancer
NCT04156360CI-TRIAL-00041519unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to detetct Circulating tumor cells(CTCs) and Cancer Associated Macrophage-Like cells (CAMLs) in patients with pulmonary nodules using a novel microfluidic CTC-detection system. Then construct an early diagnostic model for lung cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Healthy | — | UNRESOLVED | — |
| Pulmonary Nodule | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Healthy Volunteers
- label
- Patients With Pulmonary Nodule
Primary outcomes (1)
- measure
- Determination of prevalence of CTCs and CAMLs in patients with pulmonary nodules
- timeFrame
- 12 months
- description
- The number of CTCs and CAMLs will be detected in the peripheral blood of patients with pulmonary nodules using a novel microfluidic CTC-detection system.
Secondary outcomes (1)
- measure
- Determination of optimal cut-off values for screening Lung Cancer paitents
- timeFrame
- 6 months
- description
- The optimal cut-off values will be determined by the ROC analyses.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female or male, 18 years of age or older * Pulmonary nodules diagnosed by chest CT or low-dose computed tomography (LDCT) scans Exclusion Criteria: * Prior diagnosis of lung cancer or other invasive malignancy within the past 5 years
References
Publications (0)
Data not yet available
No reference posted for this study.