Clinical trial · Observational
European Registry for Myeloproliferative Neoplasms (MPNs) - Update of ERNEST Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Fondazione per la Ricerca Ospedale di Bergamo (FROM) decided to propose and promote the completion of ERNEST registry: the aim of the project is to obtain up-to-date estimates of clinical outcome of these patients in primary and secondary Myelofibrosis that have been included in the 'original' ERNEST study. The last was conducted between 2012 and beginning of 2015 including 1292 patients with Myelofibrosis, but it was interrupted in 2015 because of bankruptcy of the previous sponsor.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myelofibrosis | Primary Myelofibrosis | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Number of death
- timeFrame
- 18 years
- description
- Overall Survival
Secondary outcomes (3)
- measure
- Number of patients with evolution to acute leukemia (AL)
- timeFrame
- 18 years
- description
- Occurrence of AL from diagnosis to last observation
- measure
- Number of patients with secondary tumor (ST)
- timeFrame
- 18 years
- description
- Occurrence of ST from diagnosis to last observation
- measure
- Number of patients with cardiovascular (CV) complications
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * previous registration in the ERNEST registry (2012 - 2014) * diagnosis of MF performed between January 2001 and 2012 December * Signed informed consent to continue participation in the registry Exclusion Criteria: None
References
Publications (0)
Data not yet available