Clinical trial · Observational
C-protein Reactive for the Detection of Anastomotic Leakage After Surgery for Digestive Cancer
Diagnosis Accuracy of the C-protein Reactive for the Detection of Anastomotic Leakage After Surgery for Digestive Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to investigate the diagnostic accuracy of the C Protein Reactive (CRP) for the detection of Anastomotic leakage after surgery for digestive cancer. The standard protocol in our unit is to measure the CRP on the second and fourth postoperative day. The main aim of the study is to investigate the diagnostic accuracy of the ratio CRP on the fourth postoperative day on CRP on the second postoperative day (CRP\_D4/CRP\_D2). Secondary outcomes are the diagnosis accuracy of the CRP\_D4 and CRP\_D2.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anastomotic Leak | — | UNRESOLVED | — |
| C-Reactive Protein | — | UNRESOLVED | — |
| Digestive System Neoplasm | Digestive System Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| C-reactive protein | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Main group
- description
- One groupe in the study
- interventionNames
- Diagnostic Test: C-reactive protein
Primary outcomes (2)
- measure
- CRP_D4/CRP_D2
- timeFrame
- 30 days after surgery
- description
- Diagnosis accuracy of the ratio CRP at the fourth on the second postoperative day after surgical resection for digestive cancer, using the receiving operating curve, sensibility, specificity, positive predictive value, and negative predictive value.
- measure
- CRP_D4/CRP_D2 Colorectal
- timeFrame
- 30 days after surgery
- description
- Diagnosis accuracy of the ratio CRP at the fourth on the second postoperative day after surgical resection for colorectal cancer, using the receiving operating curve, sensibility, specificity, positive predictive value, and negative predictive value.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Surgical resection for digestive cancer * Creation of anastomosis. * at least one measurement of CRP at the second and/or fourth postoperative day. Exclusion Criteria: * Surgical resection without anastomosis creation * No measurement of CRP on the second or the fourth postoperative day.
References
Publications (0)
Data not yet available