Clinical trial · Interventional
Perioperative Analgesic Efficiency of Quadratus Lumborum Block vs Epidural in Radical Cystectomy
Perioperative Analgesic Efficiency of Ultrasound Guided Quadratus Lumborum Block Versus Epidural Analgesia in Bladder Cancer Patients Undergoing Radical Cystectomy
NCT04133051CI-TRIAL-00047328completedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is performed to measure the perioperative analgesic efficiency of bilateral quadratus lumborum block versus epidural analgesia in bladder cancer patients undergoing radical cystectomy
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pain, Postoperative | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Epidural Analgesia Using Bupivacaine 0.25% | Drug | — | UNRESOLVED |
| Quadratus Lumborum Block Using Bupivacaine 0.2% | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Quadratus Lumborum Block
- description
- 17 cases will be subjected to bilateral Ultrasound-guided Quadratus lumborum block through bilateral catheter insertion for perioperative analgesia.
- interventionNames
- Drug: Quadratus Lumborum Block Using Bupivacaine 0.2%
- type
- ACTIVE_COMPARATOR
- label
- Epidural Analgesia
- description
- 17 cases will be subjected to epidural catheter insertion for perioperative analgesia (as a control group).
- interventionNames
- Drug: Epidural Analgesia Using Bupivacaine 0.25%
Primary outcomes (4)
- measure
- Visual analogue pain (VAS) score measurement postoperatively
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * ASA II-III * Adult patients (\>18 years old) * Both sexes * Scheduled for radical cystectomy at NCI, CU Exclusion Criteria: * Patient's refusal of the study procedures * Allergy to drugs used in the study * Patients with chronic pain * Patients with coagulopathies (INR \> 1.6 or platelets count \< 50,000 cc3) * Hemodynamically unstable patients (e.g. BP \< 90/60) * Patients with local or intra-abdominal infections concerning intervention sites and septic patients
References
Publications (2)
- BACKGROUNDBlanco R, Ansari T, Girgis E. Quadratus lumborum block for postoperative pain after caesarean section: A randomised controlled trial. Eur J Anaesthesiol. 2015 Nov;32(11):812-8. doi: 10.1097/EJA.0000000000000299. PMID 26225500
- BACKGROUNDBlanco R, Ansari T, Riad W, Shetty N. Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Pain After Cesarean Delivery: A Randomized Controlled Trial. Reg Anesth Pain Med. 2016 Nov/Dec;41(6):757-762. doi: 10.1097/AAP.0000000000000495. PMID 27755488