Clinical trial · Observational
Multicentric Risk Evaluation of Autologous Fat Grafting Procedure
Multicentic Retrospective Evaluation of Risks in Mammary Carcinoma Relapse in Patients With Mammary Reconstruction and Autologous Fat Grafting
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Autologous fat grafting, also known as lipofilling, is a surgical technique consisting in the processing and transfer of adipose tissue from one area in our organism (hips, thighs) to region which in need of reconstructive and aesthetic correction. The technique is frequently used after radical or conservative mammary surgery, aiming to achieve better aesthetic results, reduce pain induced by both surgery and radiotherapy. The scientific community was widely involved in the debate regarding the use of mesenchymal/stem cells in a patient with high risk of tumor progression due to their elevated proliferative profile. This study aims to retrospectively evaluate the oncological safety in the use of lipofilling in patients who underwent oncological and reconstructive treatment in our Institute.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pain, Postoperative | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Autologous fat grafting procedure | Procedure | — | UNRESOLVED |
| Breast reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Women receiving autologous fat grafting
- description
- Women who received breast reconstruction and autologous fat grafting.
- interventionNames
- Procedure: Autologous fat grafting procedure
- Procedure: Breast reconstruction
- label
- Control
- description
- Women who received breast reconstruction only.
- interventionNames
- Procedure: Breast reconstruction
Primary outcomes (1)
- measure
- Oncological safety of autologous fat grafting
- timeFrame
- Two years
- description
- Percentage of disease relapse in loco
Secondary outcomes (3)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * female * breast carcinoma (any histological type, carcinoma in situ included) treated with radical or conservative surgery * group treated with lipofilling and group which didnt receive lipofilling * timing: retrospective evaluation of cases form 2006 to 2016, with a minimum of two year follow up Exclusion Criteria: * neoplasie different from infiltrating and in sutu breast carcinoma * in situ lobular carcinoma * patients with breast carcinoma and metastasis * lipofilling procedure used before the oncological treatment for breast carcinoma
References
Publications (0)
Data not yet available