Clinical trial · Interventional
Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation
NCT04123340CI-TRIAL-00063065IAMCOMPLETEcompletedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A pre- and postablation scan will be made intraprocedurally to investigate the feasibility of intraprocedural ablation verification assessment using coregistration software
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| HCC | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Additional intraprocedural pre-ablation CT-scan | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Additional intraprocedural CT-scan
- description
- Additional intraprocedural CT-scan
- interventionNames
- Diagnostic Test: Additional intraprocedural pre-ablation CT-scan
Primary outcomes (1)
- measure
- Feasibility of the use of co-registration software (>80%)
- timeFrame
- 1 year
- description
- The proportion of patients in whom reliable co-registration of pre- and post-ablation CT images is feasible
Secondary outcomes (3)
- measure
- Inter and intra-observer variability
- timeFrame
- 1 year
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 yrs or above * HCC very early (0) or early stage (A) according to the BCLC staging system * Either de novo or recurrent HCC (prior locoregional therapy is allowed in the study) * Candidate for percutaneous thermal ablation as discussed in a multidisciplinary tumor board. Ablation as 'bridge-to-transplant' is allowed in the study Exclusion Criteria: * Estimated GFR \<30 ml/min * Morbid obesitas or any pulmonary condition that is a contraindication to prolonged apnea and high jet-ventilation * Child Pugh C * Portal vein tumor invasion * Extrahepatic metastasis * Uncorrectable coagulopathy * Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule * Inability or unwillingness to give informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.