Clinical trial · Interventional
The Analgesic Efficacy of the Pectoral Nerves Block Versus Local Anesthetic Infiltration After Mastectomy
The Analgesic Efficacy of the Pectoral Nerves Block Versus Local Anesthetic Infiltration After Mastectomy: a Randomized, Controlled, Double Blinded Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial will include patients undergoing radical mastectomy under general anesthesia. One group of patients will receive a pectoral nerve block, done by the anesthetist under ultrasound guidance at the beginning of the invervention. The other group will receive the a wound infiltration at the end of the intervention, done by the surgeon. Investigators will compare acute pain-related outcomes and chronic pain at 3 and 6 months postoperatively.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Local infiltration | Other | — | UNRESOLVED |
| PECS block | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- PECS block
- description
- Ultrasound-guided pectoral nerve block with bupivacaine 0.5 % 30 mL before surgical incision
- interventionNames
- Other: PECS block
- type
- ACTIVE_COMPARATOR
- label
- Wound infiltration
- description
- Wound infiltration with bupivacaine 0.5 % 30 mL at the end of surgery
- interventionNames
- Other: Local infiltration
Primary outcomes (1)
- measure
- Morphine consumption
- timeFrame
- first 24 postoperative hours
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients undergoing unilateral mastectomy * American Society of Anesthesiology Physical Status I-III * Age ≥ 18 Exclusion Criteria: * Contraindications to regional anesthesia, such as infection at the surgical site * Pregnancy * History of alcohol or drug dependence/abuse * History of long term opioid intake * Chronic pain disorder
References
Publications (0)
Data not yet available