Clinical trial · Observational
Meningiomas and Treatment With CYPROTERONE ACETATE or Progestin
Meningiomas and Treatment With CYPROTERONE ACETATE or Progestin: Retrospective Study in Patients Followed at the CHRU of Brest
NCT04109404CI-TRIAL-00041110MAPcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Investigators observe an increase risk of meningioma in patient treated by CYPROTERONE ACETATE or other form of progestin. Investigatorsdiscribe caractéristics of meningioma and treatement of the patients follow up in CHRU of Brest
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Meningioma | Meningioma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Diagnosis of meningiomas caracteristics
- timeFrame
- 12 months
- description
- meningiomas caracteristics in patient treated with CYPROTERONE ACETATE or Progestin description
Secondary outcomes (1)
- measure
- prescription status of progestogenic treatment
- timeFrame
- 12 months
- description
- indications, duration of treatment, name and type of treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * minimum 18 years * medical follow up in CHRU of Brest * treated by CYPROTERONE ACETATE and/or CHLORMADINONE ACETATE NOMEGESTROL ACETATE, PROGESTERONE , DYDROGESTERONE PROMEGESTONE , NORETHISTERONE, LEVONORGESTREL , oestroprogestogenic contraception * meningioma after treatement by progestin or CYPROTERONE ACETATE Exclusion Criteria: * history ofbreast cancer * history of cerebral radiotherapy * history of neurofibromatosis * meningioma before treatement by progestin or CYPROTERONE ACETATE * minor patient
References
Publications (2)
- BACKGROUNDBernat AL, Oyama K, Hamdi S, Mandonnet E, Vexiau D, Pocard M, George B, Froelich S. Growth stabilization and regression of meningiomas after discontinuation of cyproterone acetate: a case series of 12 patients. Acta Neurochir (Wien). 2015 Oct;157(10):1741-6. doi: 10.1007/s00701-015-2532-3. Epub 2015 Aug 12. PMID 26264069
- BACKGROUNDS. Froelich, "Does cyproterone acetate promote multiple meningiomas?," 2009.