Clinical trial · Interventional
NIR and Skin Cancer Margins
Near-infrared Heating of Skin to Delineate Non-melanoma Skin Cancer Lesions: a Pilot Study.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
We aim to determine whether the application of near-infrared radiation via standard heat lamp to non-melanoma skin lesions (such as basal cell carcinomas) before surgical excision is able to better delineate the lesion and surgical margins. If found to do so, pre-heating of skin lesions could lead to more specimens with negative margins. Patients presenting to the tertiary care centre skin cancer clinic for excision of skin cancer will be approached and offered to participate in the study.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non-melanoma Skin Cancer | Skin Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Near-infrared heating | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Standard of care (control)
- description
- This will be the standard of care group. The excision of the non-melanoma skin cancer will be based on standard visual inspection with 4-6mm margins.
- type
- EXPERIMENTAL
- label
- NIR heating
- description
- This will be the NIR heating group, where the excision of the non-melanoma skin cancer will be based on the lesion margins based on the application of near-infrared radiation (with 4-6mm margins).
- interventionNames
- Radiation: Near-infrared heating
Primary outcomes (1)
- measure
- Margin status
- timeFrame
- 3 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: The patient population includes individuals with a nonmelanotic cervicofacial cutaneous malignancy referred to a tertiary care skin cancer clinic for definitive treatment. Patients must have: * Histologically confirmed nonmelanotic cutaneous malignancies, either basal cell or squamous cell carcinoma * No prior treatment with investigational agents * Ability to tolerate intended treatment Patient's age is greater than or equal to 18 years Exclusion Criteria: * Prior radiation therapy or photodynamic therapy to the area with the NMSC lesion * Patients with a history of cutaneous photosensitization * Unable to consent
References
Publications (0)
Data not yet available