Frequency of Cachexia in Ambulatory Cancer Patients and Psychological Burden in Patients and Their Primary Caregivers

Inclusion Criteria:

1. \[Patient\] Patients visiting the Supportive Care Clinic (SCC) for a consultation or a follow up.
2. \[Patient\] Patients who can identify a primary caregiver.
3. \[Patient\] Diagnosis of advanced cancer defined as locally advanced, recurrent, or metastatic.
4. \[Patient\] Be able to read and speak English.
5. \[Patient\] 18 years of age or older.
6. \[Caregiver\] Be identified or self-identified as a primary caregiver of the patient.
7. \[Caregiver\] Provide informed consent
8. \[Caregiver\] Be able to read and speak English.
9. \[Caregiver\] 18 years of age or older.
10. \[Caregiver\] Caregivers who are not able to complete the questionnaire on the day of patients' SCC visit must be willing to engage in a telephone questionnaire with research staff within 60 days of the patient's enrollment.

Exclusion Criteria:

1. \[Patient\] Refusal to participate in this study. This study requires both patient and caregiver enrollment.
2. \[Patient\] Patients with no caregiver or only paid caregivers.
3. \[Patient\] Patients with cognitive impairment as identified by research staff, treating physician or nurse (Memorial Delirium Assessment Scale score of \>/= 7).
4. \[Caregiver\] Refusal to participate in this study. This study requires both patient and caregiver enrollment.
5. \[Caregiver\] Not a primary caregiver or is a paid caregiver.
6. \[Caregiver\] Evidence of cognitive impairment, as determined based on orientation questions pertaining to the date, day of the week, time, and place