Clinical trial · Interventional
Exparel Injection Effect on Postoperative Opioid Usage
Intraoperative Injection of Exparel Effect on Postoperative Opioid Use in Thyroid and Parathyroid Surgery
NCT04085913CI-TRIAL-00079219unknownEarly Phase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The question proposed by this study, is one of patient outcomes. Does intraoperative injection of Exparel decrease postoperative use of opioid pain medications in patients undergoing thyroid and parathyroid surgery? The trial seeks to assess the effect that Exparel has on postoperative pain control.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Parathyroid Adenoma | — | UNRESOLVED | — |
| Thyroid | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bupivacaine Hydrochloride-EPINEPHrine | Drug | — | UNRESOLVED |
| Lidocaine Epinephrine | Drug | — | UNRESOLVED |
| Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Current Practice
- description
- Thyroid or parathyroid surgery with local injection of lidocaine and epinephrine preincision, as is current practice.
- interventionNames
- Drug: Lidocaine Epinephrine
- type
- EXPERIMENTAL
- label
- Bupivicaine HCL
- description
- Thyroid or parathyroid surgery with local injection of bupivicaine HCL and Epinephrine preincision.
- interventionNames
- Drug: Bupivacaine Hydrochloride-EPINEPHrine
- type
- EXPERIMENTAL
- label
- Exparel Injection
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients over the age of 18 years Patients requiring parathyroid/thyroid surgery based on the standard of care English as primary language Exclusion Criteria: * Patients under the age of 18 years Patients with previous history of opioid abuse Patients with a true allergy to any local anesthetic Patients with a true allergy to any opioid
References
Publications (0)
Data not yet available
No reference posted for this study.