Microwave Ablation for Uterine Fibroids

Inclusion Criteria:

1. Symptomatic fibroids with or without focal adenomyoma
2. Female gender
3. Age between 30 and 50
4. Pre or peri menopausal with FSH less than 40 mIU/ml
5. Negative urine pregnancy test
6. Uterine size less than 22 weeks based on physical exam assessment
7. Dominant intramural fibroid greater than or equal to 3 cm and less than or equal to 10 cm on imaging.
8. Good health other than history of leiomyomas. Chronic medications may be acceptable at the discretion of the research team.
9. Are using abstinence, mechanical (condoms, diaphragms) or sterilization methods of contraception and are willing to continue using them throughout the study.
10. Willing and able to give informed consent.
11. Willing and able to comply with study requirements.
12. Normal menstrual cycle with endometrial pathology excluded

Exclusion Criteria:

1. History of or current thromboembolic event (deep vein thrombosis, pulmonary embolus, stroke)
2. Other pelvic pathology as indicated by history or MR imaging such as endometriosis, ovarian tumor, acute or chronic pelvic inflammatory disease
3. Pregnant or Positive pregnancy test
4. Unexplained vaginal bleeding
5. Untreated severe cervical dysplasia
6. Abnormal adnexal /ovarian mass
7. Intrauterine device
8. Known recent rapid growth of fibroids, defined as a doubling in size in 6 months
9. Known bleeding tendency
10. Contraindication to MRI due to severe claustrophobia or implanted metallic device.