Clinical trial · Observational
Sedation Versus No Sedation for Detection Rates of Precancerous Lesions and Cancer
Sedation Versus No Sedation for Diagnostic Esophagogastroduodenoscopies and Detection Rates of Precancerous Lesions and Cancer: a Case-control Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The influence of sedation on the endoscopic detection rate of the precancerous lesions and cancer of upper digestive system has not been assessed. In the daily medical routine of China, patients have the right to choose the sedation style according to his or her own situation, whose detailed endoscopic data of patients are recorded in the endoscopy quality control system. The aim of this research is to detect whether the use of sedation can help improve detection rate of precancerous lesions and cancer of upper digestive system.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early Detection of Cancer | Digestive System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sedation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- No sedation
- description
- The group of patients who did endoscopies without sedation.
- label
- Sedation
- description
- The group of patients who did endoscopies with sedation.
- interventionNames
- Other: Sedation
Primary outcomes (1)
- measure
- Detection rate of precancerous lesions and cancer of upper digestive system improvement
- timeFrame
- 2020
- description
- Detection rate of precancerous lesions and cancer of upper digestive system improvement
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged more than 18 years with or without GI symptoms attending for endoscopy from 2012 to 2019. Exclusion Criteria: * Patients unable to cooperated the endoscopy or unable to complete it. People with endoscopy contraindications are naturally excluded.
References
Publications (1)
- DERIVEDZhou J, Li Z, Ji R, Wang P, Zhang A, Wu K, Liu C, Niu Q, Chu Y, Su X, Zuo X, Li Y. Influence of Sedation on the Detection Rate of Early Cancer and Precancerous Lesions During Diagnostic Upper Gastrointestinal Endoscopies: A Multicenter Retrospective Study. Am J Gastroenterol. 2021 Jun 1;116(6):1230-1237. doi: 10.14309/ajg.0000000000001201. PMID 34074827