Clinical trial · Interventional
Effectiveness of CGA on QoL in Older Patients With Cancer Receiving Systemic Therapy
The Effectiveness of Patient Coaching Within the Comprehensive Geriatric Assessment Process on Quality of Life in Older Patients With Cancer Receiving Systemic Therapy: a Multicenter Randomized Controlled Trial
NCT04069962CI-TRIAL-00065127G-oncoCOACHcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The G-oncoCOACH study aims to evaluate the effectiveness of the Comprehensive Geriatric Assessment (CGA) process coordinated by a geriatric team in combination with intensive patient coaching compared to the current standard of care, which is CGA coordinated by an oncology team.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Comprehensive Geriatric Assessment | — | UNRESOLVED | — |
| Geriatrics | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CGA coordination by geriatric team including intensive patient coaching and follow-up | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control group
- description
- Patients in the control group will receive CGA coordinated by the oncology team as standard of care, including geriatric recommendations for interventions communicated to the treating physician (eg. referral to the social worker, psychologist, dietician).
- type
- EXPERIMENTAL
- label
- Intervention group
- description
- Patients in the intervention group, the CGA including geriatric recommendations for interventions will be coordinated by the geriatric team and will be complemented with patient coaching.
- interventionNames
- Behavioral: CGA coordination by geriatric team including intensive patient coaching and follow-up
Primary outcomes (1)
- measure
- Quality of Life (QoL): EORTC QLQ-C30
- timeFrame
- QoL at 6 months since the start of the systemic therapy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * patients aged 70 years and older * diagnosis of cancer (solid tumors) * starting systemic therapy (chemotherapy, immunotherapy, targeted therapy or hormonal therapy) * curative intent (neo-adjuvant / adjuvant / concomitant / other) * palliative intent (first line / second line) * patients must be able to comply with the study procedures * physician-estimated life expectancy must be more than 6 months Exclusion Criteria: * patients with antihormonal monotherapy * previous participation in geriatric intervention studies * patients included in clinical trials with non-registered anticancer drugs
References
Publications (1)
- DERIVEDKenis C, Peeters L, Laethem L, De Cock J, Compte N, Flamaing J, Milisen K, Fagard K, Lobelle JP, Laenen A, Decoster L, Wildiers H. Effectiveness of comprehensive geriatric assessment with extensive patient coaching for improving quality of life in older patients with solid tumours receiving systemic therapy (G-oncoCOACH): a multicentre randomised controlled trial. Lancet Healthy Longev. 2025 Aug;6(8):100743. doi: 10.1016/j.lanhl.2025.100743. Epub 2025 Aug 13. PMID 40818480