Clinical trial · Interventional
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
Effects of a Protein-rich Individualized Nutritional Therapy Combined With Different Time-efficient Exercise Programs on Physical Fitness, Inflammation and Muscle Status in Cancer Patients Undergoing Curative or Palliative Anti-cancer Treatment
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular fitness), inflammation, and muscle mass/body composition in patients with malignant disease undergoing curative or palliative anti-cancer treatment
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Cancer Cachexia | — | UNRESOLVED | — |
| Inflammation | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Combined HIIT and Resistance Training (Combi) | Other | — | UNRESOLVED |
| High-intensity interval training (HIIT) | Other | — | UNRESOLVED |
| Resistance Training | Other | — | UNRESOLVED |
| WB-EMS | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Resistance Training (RT)
- description
- Individualized, protein-rich nutritional therapy combined with resistance training
- interventionNames
- Other: Resistance Training
- type
- EXPERIMENTAL
- label
- WB-EMS
- description
- Individualized, protein-rich nutritional therapy combined with whole-body electromyostimulation (WB-EMS)
- interventionNames
- Other: WB-EMS
- type
- EXPERIMENTAL
- label
- High-intensity interval training (HIIT)
- description
- Individualized, protein-rich nutritional therapy combined with high-intensity interval training (HIIT)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * malignant disease (solid or hematological cancer): head and neck cancer, colorectal carcinoma, small intestinal cancer, gastric cancer, oesophageal cancer, pancreas carcinoma, liver cell carcinoma, cholangiocarcinoma, lung cancer, breast cancer, cervix cancer, ovarian cancer, prostate cancer, renal cell carcinoma, malignant melanoma, patients with leukaemia and malignant lymphomas or Graft-versus-Host-Disease after bone marrow transplantation * ongoing or planned curative or palliative anti-cancer therapy * ECOG-Status 0-2 Exclusion Criteria: * simultaneous participation in other nutritional or exercise intervention Trials * bone metastases with high fracture risk * cardiovascular disease * use of anabolic medications * epilepsy * severe neurological or rheumatic diseases * skin lesions in the area of electrodes * energy active metals in body * pregnancy * acute vein thrombosis
References
Publications (1)
- DERIVEDReljic D, Herrmann HJ, Jakobs B, Dieterich W, Mougiakakos D, Neurath MF, Zopf Y. Feasibility, Safety, and Preliminary Efficacy of Very Low-Volume Interval Training in Advanced Cancer Patients. Med Sci Sports Exerc. 2022 Nov 1;54(11):1817-1830. doi: 10.1249/MSS.0000000000002989. Epub 2022 Jul 8. PMID 35868017