Clinical trial · Observational
Prediction of the Risk of Biochemical Relapse After Radical Prostatectomy for Prostate Cancer Using Radomics on Pre-therapeutic MRI
NCT04063800CI-TRIAL-00040564PREBOPcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
With 50% of post-operative biochemical failure, efficient predictive models are needed to guide post-operative management. Radiomic features are quantitative features extracted from medical imaging, supposed to be correlated with tumor heterogeneity. We aim to build and test three predictive models (clinical, radiomic and combined models).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostatic Adenocarcinoma | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Prediction of biochemical failure
- timeFrame
- From the date of surgery until data collection (up to 100 months)
- description
- Comparison of AUCs between each predictive model
Secondary outcomes (1)
- measure
- Prediction of survival without biochemical failure
- timeFrame
- From the date of surgery until data collection (up to 100 months)
- description
- Survival analysis: comparison of Kaplan-Meier curves
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 18yo * Patients underwent radical prostatectomy * High-risk prostate cancers: at least 1 criteria (pt3a/pT3b/pT4, R1, Gleason score \> 7) Exclusion Criteria: * No available pre-operative MRI * No analyzable pre-operative MRI * proof of lymph-node involvement (cN1/2 or pN1/2) * post-operative PSA \> 0.04ng/mL
References
Publications (0)
Data not yet available
No reference posted for this study.