Clinical trial · Observational
Hepatocarcinoma Recurrence on the Liver Study - Part2
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Rationale for the trial. To evaluate the impact of surgery on hepatocarcinoma recurrence. Thus, to evaluate the impact of different clinical, radiological, histopathological variables on recurrence after surgical treatment. The nature of this study will allow to observe, over time, the distribution of the considered collection variables, allowing a strictly observational monitoring of possible associations able to suggest models or interpretations, which can then be the basis for the construction of prospective and randomized studies.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cirrhosis | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
| Recurrence Tumor | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| liver resection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Disease-free-Survival
- timeFrame
- 15 years of follow-up
- description
- Disease Free Survival: the time between surgery and event of recurrence or death measured in months. If no event, patients will be censored at the last available follow-up date.
- measure
- Overall Survival
- timeFrame
- 15 years of follow-up
- description
- The time from surgery to death measured in months. If no event, patients will be censored at the last available follow-up.
Secondary outcomes (2)
- measure
- Localization of the recurrence
- timeFrame
- 15 years of follow-up
- description
- Presence of relapse disease on the surgical cut surface rather than at distance
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * No age limit. * Hepatocarcinoma diagnosis confirmed at histological specimen * Every single patients with first HCC diagnosis or with a recurrence/persistence disease evaluated and treated with surgery at the participating center. * the assessment for patient enrollment must have been performed starting from 02/02/2019. Exclusion Criteria: * Surgery as a downstaging therapy for transplant * Patients treated with surgery in case of not-curative intent (palliation, best supportive care, etc). * Histopathological specimen of combined liver primary neoplasms (e.g. "hepatocholangiocarcinoma''). * Patients with other tumors in the previous past.
References
Publications (0)
Data not yet available