Clinical trial · Interventional
Tubeless NOSES Versus Laparoscopic Radical Resection for Rectosigmoid Cancers
A Perspective Study to Compare the Tubeless NOSES and Traditional Laparoscopic Radical Resection in Rectosigmoid Cancers (CORNER)
NCT04037956CI-TRIAL-00057434CORNERrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to evaluate the short-term and long-term results after Tubeless NOSES for the resection of Rectosigmoid Cancers compared with traditional laparoscopic radical resection.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectosigmoid Cancers | Malignant Rectosigmoid Neoplasm | ALIAS | 0.90 |
| Traditional Laparoscopic Radical Resection | — | UNRESOLVED | — |
| Tubeless NOSES | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| traditional laparoscopic radical resection | Procedure | — | UNRESOLVED |
| Tubeless NOSES | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Tubeless NOSES
- description
- Patients receive Tubeless NOSES.
- interventionNames
- Procedure: Tubeless NOSES
- type
- ACTIVE_COMPARATOR
- label
- traditional laparoscopic
- description
- Patients receive traditional laparoscopic radical resection.
- interventionNames
- Procedure: traditional laparoscopic radical resection
Primary outcomes (1)
- measure
- 3-year disease free survival rate
- timeFrame
- 36 months after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Histologically or cytologically confirmed Rectosigmoid Cancers 2. Clinical stage at T 1-3 N0-2 M0 3. Tumors on peritoneal reflection，Tumor size is no more than 3 cm 4. Eastern Cooperative Oncology Group (ECOG) scale is 0-2 5. American Society of Anesthesiologists (ASA) score is Ⅰ-Ⅲ 6. BMI ≤ 30 kg/m2 7. Subjects must be willing and able to comply with scheduled visits, treatment schedule,and laboratory testing. Exclusion Criteria: 1. Heart, lung, liver or renal or any organ function that are intolerance for surgery 2. History of treated colorectal malignant disease 3. Subjects with medical condition, such as intestinal obstruction, intestinal perforation, bleeding, requires emergency surgery 4. Subjects with previous malignancies 5. History of inflammatory bowl disease(IBD) or familial adenomatous polyposis (FAP) 6. Treatment with any other clinical trial within 28 days prior to randomization 7. History of severe mentally disease 8. pregnant or lactating women 9. The researchers believe that the patients are unsuitable to participate in the researchers with other cases.
References
Publications (0)
Data not yet available
No reference posted for this study.