Clinical trial · Observational
Prevalence of Intrauterine Adhesions After Myomectomy
Prevalence of Intrauterine Adhesions After Myomectomy: A Prospective Multicenter Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective, multicenter, observational study evaluated the prevalence of intrauterine adhesions after laparoscopic or laparotomic myomectomy and investigated clinical and surgical factors associated with their occurrence. Consecutive women who underwent laparoscopic or laparotomic myomectomy were considered eligible and were approached for enrollment. Women who provided informed consent were included in the study. All included women underwent myomectomy and postoperative management according to routine clinical practice. All enrolled women underwent office diagnostic hysteroscopy three months after surgery to assess the presence of intrauterine adhesions. Clinical characteristics, surgical details of the myomectomy, and hysteroscopic findings were prospectively collected in an anonymized database.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myoma;Uterus | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Diagnostic hysteroscopy | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Laparotomic myomectomy
- description
- Women undergoing uterine myomectomy by open surgery (laparotomy).
- interventionNames
- Diagnostic Test: Diagnostic hysteroscopy
- label
- Laparoscopic myomectomy
- description
- Women undergoing uterine myomectomy by laparoscopy.
- interventionNames
- Diagnostic Test: Diagnostic hysteroscopy
Primary outcomes (1)
- measure
- Prevalence of intrauterine adhesions
- timeFrame
- 3 months after myomectomy
- description
- Proportion of enrolled women with intrauterine adhesions identified by office diagnostic hysteroscopy. Intrauterine adhesions were defined according to the European Society of Gynecological Endoscopy (ESGE) criteria.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of one or more uterine myomas * Desire to preserve fertility/uterus * Myomectomy (by laparotomy or laparoscopy) Exclusion Criteria: * Adults unable to consent * Pregnant women * Prisoners * History of previous intrauterine procedures such as dilation and curettage * History of known intrauterine adhesions * History of documented pelvic inflammatory disease * History of endometritis (acute or chronic) * Hysteroscopic myomectomy
References
Publications (1)
- RESULTLagana AS, Garzon S, Dababou S, Uccella S, Medvediev M, Pokrovenko D, Babunashvili EL, Buyanova SN, Schukina NA, Shcherbatykh Kaschchuk MG, Kosmas I, Licchelli M, Panese G, Tinelli A. Prevalence of Intrauterine Adhesions after Myomectomy: A Prospective Multicenter Observational Study. Gynecol Obstet Invest. 2022;87(1):62-69. doi: 10.1159/000522583. Epub 2022 Feb 15. PMID 35168241