Clinical trial · Observational
Gastric Cancer Risk Factors Knowledge in European and Latinamerican Population
Interventional Study at the Primary and Secondary Levels of Prevention for Knowledge Regarding GC Risk Factors in EU and CELAC Populations
NCT04019808CI-TRIAL-00076950LEGACY-3completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is divided into two parts: Part 1: An interventional study, with a pre-post study design to determinate the grade of knowledge of established GC risk factors. Part 2: An observational study to know impact on prevalence and infection eradication of H. pylori
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- knowledge GC risk factors and symptoms
- timeFrame
- 3 years
- description
- Compare the results obtained through a knowledge of CG risk factors by study-specific questionnaire before and after an educational intervention
- measure
- H. pylori prevalence and drug resistance
- timeFrame
- 3 years
- description
- Generate an H. pylori registry, to know its impact on prevalence and infection eradication rate at months 6th, 12th, 24th and 36th.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Part A: Educational Intervention Inclusion criteria * Subjects \>18 years old, from EU and CELAC countries participating in this study. * Has given and signed the IC to participate in this study. Exclusion criteria * Subjects who have received some prior preparation (Cancer Gastric Information). * Subjects who have previous Knowledge in Gastric Cancer (Example, near relatives who have suffered Gastric Cancer Part B: H. pylori Register Inclusion criteria * Subjects ≥18 years old diagnose from H. pylori infection and treated at participant sites * Has given and signed the IC. Exclusion criteria * Subjects with chronic gastritis without confirmed diagnose of H. pylori infection, pathologically of by urease test. * Patient's with CG diagnosis (including gastroesophageal junction cancer).
References
Publications (2)
- DERIVEDCarbonell-Asins JA, Jimenez-Marti E, Romero S, Garcia E, Miralles-Marco A, Lopez B, Huerta M, Caballero C, Boggino H, Gauna C, Acevedo-Funes OB, Nunez GB, Cespedes-Cardozo CM, Fernandez-Figueroa EA, Ortiz-Olvera N, Ruiz-Garcia E, Carneiro F, Barros R, Figueiredo C, Ferreira RM, Groen-van Schooten TS, van Santvliet D, Derks S, Luca R, Alsina M, Riquelme A, Cervantes A, Fleitas T. Implementation of an Educational Intervention for Gastric Cancer Awareness in the General Population in CELAC and Europe: A Strategy Proposed by the LEGACy Consortium. J Cancer Educ. 2025 Oct;40(5):804-811. doi: 10.1007/s13187-025-02578-2. Epub 2025 Feb 13. PMID 39939517
- DERIVEDvan Schooten TS, Derks S, Jimenez-Marti E, Carneiro F, Figueiredo C, Ruiz E, Alsina M, Molero C, Garrido M, Riquelme A, Caballero C, Lezcano E, O'Connor JM, Esteso F, Farres J, Mas JM, Lordick F, Vogt J, Cardone A, Girvalaki C, Cervantes A, Fleitas T; members of LEGACy consortium. The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally. BMC Cancer. 2022 Jun 13;22(1):646. doi: 10.1186/s12885-022-09689-9. PMID 35692051