Clinical trial · Interventional
Percutaneous Vertebroplasty Using Rotary Cutter for Bone Metastases
Percutaneous Vertebroplasty Using Rotary Cutter for Treating Bone Metastases
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Percutaneous vertebroplasty has been applied widely to treat bone metastases. The injected cement may strengthen the affected bone to prevent pathological fractures and relieve the pain. Moreover, the thermal reaction (70°C) due to polymerisation of cement also contributes to tumour destruction. The cement dose and diffusion pattern may be significant factors for the treatment efficacy, which can be affected by the inner pressure of the metastases. The investigators will apply a rotary cutter to destroy the structure of metastases to alleviate the pressure in the metastases. Then, more cement will be injected, which may effectively interdigitates with the surrounding bone and generate more thermo to kill the tumor cells.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional Percutaneous Vertebroplasty | Device | — | UNRESOLVED |
| Percutaneous Vertebroplasty with Rotary Cutter | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Conventional Percutaneous Vertebroplasty
- description
- The cement is injected after the successful puncture.
- interventionNames
- Device: Conventional Percutaneous Vertebroplasty
- type
- EXPERIMENTAL
- label
- Percutaneous Vertebroplasty with Rotary Cutter
- description
- The rotary cutter is applied to destroy the metastatic lesion before coment injection.
- interventionNames
- Device: Percutaneous Vertebroplasty with Rotary Cutter
Primary outcomes (1)
- measure
- Back pain: Visual analogue scales system
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Imaging-proven and pathology-proven metastases 2. Intractable pain with neurologic dysfunction Exclusion Criteria: 1\. Poor general condition without tolerance of surgery
References
Publications (0)
Data not yet available